Problem:

• You have ASP.NET website on Windows.
• Your website application pool name is mysite.com.
• Your website physical location is D:\inetpub\wwwroot\mysite.com.
• Your website physical data location is D:\mysite_data.
• Your website users cannot upload or modify website files.
• Your website users cannot upload or modify website data files.

Solution:

1. Open cmd.exe as Administrator and execute the command below.

icacls "D:\inetpub\wwwroot\mysite.com" /grant "IIS AppPool\mysite.com":(OI)(CI)F /T
icacls "D:\mysite_data" /grant "IIS AppPool\mysite.com":(OI)(CI)F /T

This command give full permissions against D:\inetpub\wwwroot\mysite.com  and all sub-directories and files, and against D:\mysite_data  and all sub-directories and files to mysite.com user.

2. Alternatively you can execute the command below.

icacls "D:\inetpub\wwwroot\mysite.com" /grant IIS_IUSRS:F /t
icacls "D:\mysite_data" /grant IIS_IUSRS:F /t

This command give full permissions against D:\inetpub\wwwroot\mysite.com  and all sub-directories and files, and against D:\mysite_data  and all sub-directories and files to IIS_IUSRS group.

mysite.com user is part of the IIS_IUSRS group.